October 25, 2010

Dr. David Phillips
CEO and Founder
ReBuilder Medical

RE: ReBuilder^® System

On behalf of the Oncology Rehabilitation team and the Medical Staff at Midwestern Regional Medical Center, I want to personally thank you for inventing and developing the ReBuilder^® system, a fabulous medical device to help alleviate the symptoms of peripheral neuropathy. In the past, we have used traditional physical therapy electrical stimulation devices such as traditional TENS and Interferential Current (IFC), but the ReBuilder^® system provided our patients with Chemotherapy-Induced Peripheral Neuropathy (CIPN) the best and longest lasting pain relief while undergoing chemotherapy treatment.

From 2005 to 2007 we treated 124 cancer patients with CIPN who were actively undergoing chemotherapy treatment at Midwestern Regional Medical Center of which 40% reported a 30% to 50% reduction in their pain scale, 53% reporting 10% to 20% reduction in their pain scale, and 3% reporting 50% or more reduction in their pain scale, and only 4% reported no change.

With these remarkable results (96% success rate) the ReBuilder System is now being used across all four CTCA sites in Tulsa, Phoenix, Philadelphia, and Chicago – touching and helping more oncology patients relieve their CIPN symptoms. This calendar year alone, between all four sites, we have treated over 300 patients successfully.

We believe in your product’s ability to alleviate CIPN symptoms for cancer patients receiving chemotherapy. Patients have reduced or stopped taking pain medicine such as Gabapentin and Lyrica for CIPN.

At CTCA…

“It is only… and always will be…..about the patient.” Richard Stephenson, Chairman of the Board at Cancer Treatment Centers of America

Subjective Patient’s Response

Neuropathy & Clinical Research

Chemotherapy is often used to treat different types of cancer. Unfortunately, the use of chemicals to breakdown certain parts of the body to kill cells will ultimately affect all fast dividing cells in the body. As a result several side-effects can and often do occur:

• Pain
• Nausea and vomiting
• Diarrhea or constipation
• Anemia
• Malnutrition
• Hair loss
• Memory loss
• Depression of the immune system, hence (potentially lethal) infections and sepsis
• Weight loss or gain
• Hemorrhage
• Secondary neoplasms
• Cardiotoxicity
• Hepatotoxicity
• Nephrotoxicity
• Ototoxicity

There are currently about 15 widely used treatments for neuropathy. However, more than half of these are treatments that involve some form of medicine to be relied upon. Thus, this results in more side-effects, the very things that caused the problem in the first place.

In some cases, hospitals are at risks when symptoms like neuropathy occur. In cases where there is a misuse, misdiagnosis, or an overdose, the hospital may find themselves in the middle of a lawsuit by the person who received the treatment. The patient has the right to seek council if a misuse of treatment has cause neuropathy or other related lasting effects.

Most of the common reported symptoms are:

• Numbness
• Tingling
• Pain
• Hypersensitivity
• Stiffness

On average most patients are seen 1-2 x prior to going home with a home unit.

They continue to self treat at home. Instructions are given to use it daily up to 3x/day.

No actual data at this time for follow up. This will be the next step.